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Cellosaurus RAW264.7 clone J8 (CVCL_C6WY)

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Cell line name RAW264.7 clone J8
Synonyms J8.2g6
Accession CVCL_C6WY
Resource Identification Initiative To cite this cell line use: RAW264.7 clone J8 (RRID:CVCL_C6WY)
Comments Characteristics: Compared to parent cell line, does not form multinucleated TRAP-positive cells or exhibit other osteoclast-characteristics (PubMed=31947698).
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0493 (RAW 264.7)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=31947698; DOI=10.3390/ijms21020538; PMCID=PMC7013577
Laia Mira-Pascual, Anh N. Tran, Goran Andersson, Tuomas Nareoja, Pernilla Lang;
A sub-clone of RAW264.7-cells form osteoclast-like cells capable of bone resorption faster than parental RAW264.7 through increased de novo expression and nuclear translocation of NFATc1.
Int. J. Mol. Sci. 21:538.1-538.19(2020)

Cross-references
Encyclopedic resources Wikidata; Q117704817
Entry history
Entry creation21-Mar-2023
Last entry update29-Jun-2023
Version number2