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Cellosaurus GSC-83/ALDH1A3-KO.1.2 (CVCL_C6J3)

[Text version]
Cell line name GSC-83/ALDH1A3-KO.1.2
Accession CVCL_C6J3
Resource Identification Initiative To cite this cell line use: GSC-83/ALDH1A3-KO.1.2 (RRID:CVCL_C6J3)
Comments Group: Cancer stem cell line.
Knockout cell: Method=CRISPR/Cas9; HGNC; 409; ALDH1A3.
Derived from site: In situ; Brain, right temporal lobe; UBERON=UBERON_0002809.
Cell type: Mesenchymal stem cell; CL=CL_0000134.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C6IZ (GSC-83)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=34934174; DOI=10.1038/s42003-021-02949-7
Li J.-F., Garavaglia S., Ye Z.-F., Moretti A., Belyaeva O.V., Beiser A., Ibrahim M., Wilk A., McClellan S., Klyuyeva A.V., Goggans K.R., Kedishvili N.Y., Salter E.A., Wierzbicki A., Migaud M.E., Mullett S.J., Yates N.A., Camacho C.J., Rizzi M., Sobol R.W.
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.
Commun. Biol. 4:1420.1-1420.16(2021)

Cross-references
Encyclopedic resources Wikidata; Q116049105
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3