Cellosaurus cell line GSC-83/ALDH1A3-KO.1.2 (CVCL

Cross-references
Cell line name	GSC-83/ALDH1A3-KO.1.2
Accession	CVCL_C6J3
Resource Identification Initiative	To cite this cell line use: GSC-83/ALDH1A3-KO.1.2 (RRID:CVCL_C6J3)
Comments	Group: Cancer stem cell line. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:409; ALDH1A3. Derived from site: In situ; Brain, right temporal lobe; UBERON=UBERON_0002809. Cell type: Mesenchymal stem cell; CL=CL_0000134.
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_C6IZ (GSC-83)
Sex of cell	Female
Age at sampling	72Y
Category	Cancer cell line
Publications	PubMed=34934174; DOI=10.1038/s42003-021-02949-7; PMCID=PMC8692581 Jian-Feng Li, Silvia Garavaglia, Zhao-Feng Ye, Andrea Moretti, Olga V. Belyaeva, Alison Beiser, Md Ibrahim, Anna Wilk, Steve McClellan, Alla V. Klyuyeva, Kelli R. Goggans ...Show all 20 authors... , Natalia Y. Kedishvili, E. Alan Salter, Andrzej Wierzbicki, Marie E. Migaud, Steven J. Mullett, Nathan A. Yates, Carlos J. Camacho, Menico Rizzi, Robert William Sobol; Show fewer authors A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells. Commun. Biol. 4:1420.1-1420.16(2021)
Encyclopedic resources	Wikidata; Q116049105
Entry history
Entry creation	15-Dec-2022
Last entry update	19-Dec-2024
Version number	4