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Cellosaurus HeLa-C3 (CVCL_C5RL)

[Text version]
Cell line name HeLa-C3
Synonyms HeLa C3
Accession CVCL_C5RL
Resource Identification Initiative To cite this cell line use: HeLa-C3 (RRID:CVCL_C5RL)
Comments Population: African American.
Characteristics: Obtained from the parent cell line that was subjected to 3 cycles of 10 Gy of Ce-137 irradiation (CelloPub=CLPUB00727; PubMed=9374378).
Doubling time: 20.5-23 hours (PubMed=9374378).
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Transformant: NCIt; C129643; Cesium-137 gamma radiation.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

Eichholtz-Wirth H., Stoetzer O.J., Marx K.
Radiation-induced cisplatin resistance in two human cell lines.
Radioprotection 32:139-140(1997)

PubMed=9374378; DOI=10.1038/bjc.1997.555
Eichholtz-Wirth H., Stoetzer O.J., Marx K.
Reduced expression of the ICE-related protease CPP32 is associated with radiation-induced cisplatin resistance in HeLa cells.
Br. J. Cancer 76:1322-1327(1997)

Chemistry resources ChEMBL-Cells; CHEMBL3886021
Encyclopedic resources Wikidata; Q116049309
Entry history
Entry creation15-Dec-2022
Last entry update05-Oct-2023
Version number4