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Cellosaurus C3RL4 (CVCL_C5IW)

[Text version]
Cell line name C3RL4
Synonyms C3H10T1/2, RARE-Luc, clone #4
Accession CVCL_C5IW
Resource Identification Initiative To cite this cell line use: C3RL4 (RRID:CVCL_C5IW)
Comments Biotechnology: Used in a bioassay to assess chemicals for the ability to interfere with retinol signaling.
Characteristics: Expresses luciferase under the control of the retinoic acid response element (RARE) (PubMed=26820057).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0190 (C3H/10T1/2 clone 8)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line

PubMed=26820057; DOI=10.1016/j.tiv.2016.01.011
Chen Y.-L., Sakamuru S., Huang R.-L., Reese D.H., Xia M.-H.
Identification of compounds that modulate retinol signaling using a cell-based qHTS assay.
Toxicol. In Vitro 32:287-296(2016)

Encyclopedic resources Wikidata; Q116048632
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3