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Cellosaurus RUCH-2 (CVCL_C540)

[Text version]
Cell line name RUCH-2
Synonyms Ruch-2; RUCH2; Ruch2; Rhabdomyosarcoma of University Children's Hospital-2
Accession CVCL_C540
Resource Identification Initiative To cite this cell line use: RUCH-2 (RRID:CVCL_C540)
Comments Omics: Proteomics; Subcellular; Cell surface.
Omics: Transcriptomics; Microarray.
Sequence variations
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y3M
Category Cancer cell line
Publications

DOI=10.3929/ethz-a-003884990
Florence Astrid Scholl;
Identification and characterization of proteins involved in tumor formation and progression.
Thesis PhD (2000); Swiss Federal Institute of Technology Zurich; Zurich; Switzerland

PubMed=10735512; DOI=10.1054/bjoc.1999.1069; PMCID=PMC2363357
Florence Astrid Scholl, David R. Betts, Felix K. Niggli, Beat W. Schafer;
Molecular features of a human rhabdomyosarcoma cell line with spontaneous metastatic progression.
Br. J. Cancer 82:1239-1245(2000)

PubMed=12068308; DOI=10.1038/nature00766
Helen R. Davies, Graham Robert Bignell, Charles Cox, Philip J. Stephens, Sarah Edkins, Sheila Clegg, Jon W. Teague, Hayley Woffendin, Mathew J. Garnett, William Bottomley, Neil Davis ...Show all 52 authors... , Ed Dicks, Rebecca Ewing, Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry Austin Gusterson, Colin S. Cooper, Janet M. Shipley, Darren Hargrave, Kathy Pritchard-Jones, Norman J. Maitland, Georgia Chenevix-Trench, Gregory J. Riggins, Darell Doty Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne M. Flanagan, Andrew Nicholson, Judy W.C. Ho, Suet Yi Leung, Siu Tsan Yuen, Barbara L. Weber, Hilliard Foster Seigler, Timothy L. Darrow, Hugh F. Paterson, Richard Marais, Christopher John Marshall, Richard Wooster, Michael Rudolf Stratton, P. Andrew Futreal; Show fewer authors
Mutations of the BRAF gene in human cancer.
Nature 417:949-954(2002)

PubMed=12904596; DOI=10.1203/01.PDR.0000086901.29111.2A
Elke Kleideiter, Matthias Schwab, Ulrike Friedrich, Ewa Koscielniak, Beat W. Schafer, Ulrich Klotz;
Telomerase activity in cell lines of pediatric soft tissue sarcomas.
Pediatr. Res. 54:718-723(2003)

PubMed=19235922; DOI=10.1002/gcc.20655
Edoardo Missiaglia, Joanna Selfe, Mohamed Hamdi, Daniel Williamson, Gerben Schaaf, Cheng Fang, Jan Koster, Brenda M. Summersgill, Boo Messahel, Rogier Versteeg, Kathy Pritchard-Jones ...Show all 13 authors... , Marcel Kool, Janet M. Shipley; Show fewer authors
Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development.
Genes Chromosomes Cancer 48:455-467(2009)

PubMed=23882450; DOI=10.3389/fonc.2013.00183; PMCID=PMC3713458
Ashley R.P. Hinson, Rosanne Jones, Lisa E.S. Crose, Brian C. Belyea, Frederic G. Barr, Corinne Mary Linardic;
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Front. Oncol. 3:183.1-183.12(2013)

PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347
Damaris Bausch-Fluck, Andreas Hofmann, Thomas Bock, Andreas P. Frei, Ferdinando Cerciello, Andrea Jacobs, Hansjoerg Moest, Ulrich Omasits, Rebekah L. Gundry, Charles Yoon, Ralph Schiess ...Show all 20 authors... , Alexander Schmidt, Paulina Mirkowska, Anetta Svitorka Hartlova, Jennifer Eileen Van Eyk, Jean-Pierre Bourquin, Rudolf Aebersold, Kenneth R. Boheler, Peter W. Zandstra, Bernd Wollscheid; Show fewer authors
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:e0121314.1-e0121314.22(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C540
Encyclopedic resources Wikidata; Q54951463
Gene expression databases GEO; GSM219755
Polymorphism and mutation databases Cosmic; 686754
Cosmic; 1309333
Proteomic databases PRIDE; PXD000589
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number16