ID   RUCH-2
AC   CVCL_C540
SY   Ruch-2; RUCH2; Ruch2; Rhabdomyosarcoma of University Children's Hospital-2
DR   cancercelllines; CVCL_C540
DR   Cosmic; 686754
DR   Cosmic; 1309333
DR   GEO; GSM219755
DR   PRIDE; PXD000589
DR   Wikidata; Q54951463
RX   DOI=10.3929/ethz-a-003884990;
RX   PubMed=10735512;
RX   PubMed=12068308;
RX   PubMed=12904596;
RX   PubMed=19235922;
RX   PubMed=23882450;
RX   PubMed=25894527;
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=12068308).
CC   Omics: Proteomics; Subcellular; Cell surface.
CC   Omics: Transcriptomics; Microarray.
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   1Y3M
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 16
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RX   DOI=10.3929/ethz-a-003884990;
RA   Scholl F.A.;
RT   "Identification and characterization of proteins involved in tumor
RT   formation and progression.";
RL   Thesis PhD (2000); Swiss Federal Institute of Technology Zurich; Zurich; Switzerland.
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RX   PubMed=10735512; DOI=10.1054/bjoc.1999.1069; PMCID=PMC2363357;
RA   Scholl F.A., Betts D.R., Niggli F.K., Schafer B.W.;
RT   "Molecular features of a human rhabdomyosarcoma cell line with
RT   spontaneous metastatic progression.";
RL   Br. J. Cancer 82:1239-1245(2000).
//
RX   PubMed=12068308; DOI=10.1038/nature00766;
RA   Davies H.R., Bignell G.R., Cox C., Stephens P.J., Edkins S., Clegg S.,
RA   Teague J.W., Woffendin H., Garnett M.J., Bottomley W., Davis N.,
RA   Dicks E., Ewing R., Floyd Y., Gray K., Hall S., Hawes R., Hughes J.,
RA   Kosmidou V., Menzies A., Mould C., Parker A., Stevens C., Watt S.,
RA   Hooper S., Wilson R., Jayatilake H., Gusterson B.A., Cooper C.S.,
RA   Shipley J.M., Hargrave D., Pritchard-Jones K., Maitland N.J.,
RA   Chenevix-Trench G., Riggins G.J., Bigner D.D., Palmieri G., Cossu A.,
RA   Flanagan A.M., Nicholson A., Ho J.W.C., Leung S.Y., Yuen S.T.,
RA   Weber B.L., Seigler H.F., Darrow T.L., Paterson H.F., Marais R.,
RA   Marshall C.J., Wooster R., Stratton M.R., Futreal P.A.;
RT   "Mutations of the BRAF gene in human cancer.";
RL   Nature 417:949-954(2002).
//
RX   PubMed=12904596; DOI=10.1203/01.PDR.0000086901.29111.2A;
RA   Kleideiter E., Schwab M., Friedrich U., Koscielniak E., Schafer B.W.,
RA   Klotz U.;
RT   "Telomerase activity in cell lines of pediatric soft tissue
RT   sarcomas.";
RL   Pediatr. Res. 54:718-723(2003).
//
RX   PubMed=19235922; DOI=10.1002/gcc.20655;
RA   Missiaglia E., Selfe J., Hamdi M., Williamson D., Schaaf G., Fang C.,
RA   Koster J., Summersgill B.M., Messahel B., Versteeg R.,
RA   Pritchard-Jones K., Kool M., Shipley J.M.;
RT   "Genomic imbalances in rhabdomyosarcoma cell lines affect expression
RT   of genes frequently altered in primary tumors: an approach to identify
RT   candidate genes involved in tumor development.";
RL   Genes Chromosomes Cancer 48:455-467(2009).
//
RX   PubMed=23882450; DOI=10.3389/fonc.2013.00183; PMCID=PMC3713458;
RA   Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G.,
RA   Linardic C.M.;
RT   "Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research:
RT   utility and pitfalls.";
RL   Front. Oncol. 3:183.1-183.12(2013).
//
RX   PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347;
RA   Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F.,
RA   Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R.,
RA   Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P.,
RA   Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.;
RT   "A mass spectrometric-derived cell surface protein atlas.";
RL   PLoS ONE 10:e0121314.1-e0121314.22(2015).
//