Cellosaurus mAb158 (CVCL_C4UY)
| Cell line name | mAb158 |
|---|---|
| Accession | CVCL_C4UY |
| Resource Identification Initiative | To cite this cell line use: mAb158 (RRID:CVCL_C4UY) |
| Comments | Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized lecanemab (BAN2401) therapeutic antibody used for the treatmen of Alzheimer disease. Monoclonal antibody isotype: IgG2a. Monoclonal antibody target: UniProtKB; P05067; Human APP (Note=Selectively binds to large, soluble Abeta protofibrils, does not bind native APP). |
| Species of origin | Mus musculus (Mouse) (NCBI Taxonomy: 10090) |
| Hierarchy | Parent: CVCL_2199 (Sp2/0-Ag14) |
| Category | Hybridoma |
| Publications | PubMed=17623042; DOI=10.1111/j.1471-4159.2007.04759.x |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q116049759 |
| Entry history | |
| Entry creation | 15-Dec-2022 |
| Last entry update | 21-Mar-2023 |
| Version number | 2 |