ID   mAb158
AC   CVCL_C4UY
DR   Wikidata; Q116049759
RX   PubMed=17623042;
CC   Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized lecanemab (BAN2401) therapeutic antibody used for the treatmen of Alzheimer disease.
CC   Monoclonal antibody isotype: IgG2a.
CC   Monoclonal antibody target: UniProtKB; P05067; Human APP (Note=Selectively binds to large, soluble Abeta protofibrils, does not bind native APP).
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_2199 ! Sp2/0-Ag14
CA   Hybridoma
DT   Created: 15-12-22; Last updated: 21-03-23; Version: 2
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RX   PubMed=17623042; DOI=10.1111/j.1471-4159.2007.04759.x;
RA   Englund H., Sehlin D., Johansson A.-S., Nilsson L.N.G., Gellerfors P.,
RA   Paulie S., Lannfelt L., Pettersson F.E.;
RT   "Sensitive ELISA detection of amyloid-beta protofibrils in biological
RT   samples.";
RL   J. Neurochem. 103:334-345(2007).
//