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Cellosaurus L8 fu-1 (CVCL_C4KT)

[Text version]
Cell line name L8 fu-1
Synonyms fu-1
Accession CVCL_C4KT
Resource Identification Initiative To cite this cell line use: L8 fu-1 (RRID:CVCL_C4KT)
Comments Characteristics: Non-fusing variant (PubMed=269441).
Virology: Expresses a C-type rat retrovirus (PubMed=269441; PubMed=6243570).
Doubling time: 14.8 +- 1.2 hours (Note=In 10% serum), 16.6 +- 2.0 hours (Note=In 1% serum) (PubMed=269441).
Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134.
Cell type: Myoblast; CL=CL_0000056.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS_0000955.
Hierarchy Parent: CVCL_4236 (L8 [Rat muscle])
Sex of cell Sex unspecified
Age at sampling <1D
Category Spontaneously immortalized cell line
Publications

PubMed=269441; DOI=10.1073/pnas.74.9.3888; PMCID=PMC431773
Stephen J. Kaufman, Christine M. Parks;
Loss of growth control and differentiation in the fu-1 variant of the L8 line of rat myoblasts.
Proc. Natl. Acad. Sci. U.S.A. 74:3888-3892(1977)

PubMed=6243570; DOI=10.1016/0014-4827(80)90128-7
Stephen J. Kaufman, Christine M. Parks, Joseph Bohn, Lia E. Faiman;
Transformation is an alternative to normal skeletal muscle development.
Exp. Cell Res. 125:333-349(1980)

PubMed=3889014; DOI=10.1083/jcb.100.6.1977; PMCID=PMC2113591
Stephen J. Kaufman, Rachel F. Foster, Keith R. Haye, Lia E. Faiman;
Expression of a developmentally regulated antigen on the surface of skeletal and cardiac muscle cells.
J. Cell Biol. 100:1977-1987(1985)

PubMed=8028596; DOI=10.1007/BF01457398
Laurence D. Cambron, Kenneth C. Leskawa;
Glycosphingolipids during skeletal muscle cell differentiation: comparison of normal and fusion-defective myoblasts.
Mol. Cell. Biochem. 130:173-185(1994)

Cross-references
Encyclopedic resources Wikidata; Q116049647
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number5