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Cellosaurus MUC-1 (CVCL_C4KG)

[Text version]
Cell line name MUC-1
Accession CVCL_C4KG
Resource Identification Initiative To cite this cell line use: MUC-1 (RRID:CVCL_C4KG)
Comments Characteristics: Established from a patient-derived xenograft also called MUC-1.
Omics: Genomics; Whole genome sequencing.
Derived from site: Metastatic; Neck, hypodermis; UBERON=UBERON_0000974+UBERON_0002072.
Sequence variations
Disease Adrenal cortex carcinoma (NCIt: C9325)
Adrenocortical carcinoma (ORDO: Orphanet_1501)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): PubMed=27764813

Markers:
AmelogeninX
CSF1PO12
D1S165615
D2S133826
D3S135816,18
D5S81811
D6S104312
D7S8208,10
D8S11798
D12S39119.3,22
D13S3179
D16S53911,14
D18S5114,18
D19S43313,14
D21S1129
FGA22,23.2
Penta D9
Penta E7,13
TH019.3
TPOX8
vWA16,17

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Publications

PubMed=27764813; DOI=10.18632/oncotarget.12685; PMCID=PMC5346714
Hantel C., Shapiro I., Poli G., Chiapponi C., Bidlingmaier M., Reincke M., Luconi M., Jung S., Beuschlein F.
Targeting heterogeneity of adrenocortical carcinoma: evaluation and extension of preclinical tumor models to improve clinical translation.
Oncotarget 7:79292-79304(2016)

PubMed=33981288; DOI=10.3389/fendo.2021.669426; PMCID=PMC8108132
Rossini E., Tamburello M., Abate A., Beretta S., Fragni M., Cominelli M., Cosentini D., Hantel C., Bono F., Grisanti S., Poliani P.L., Tiberio G.A.M., Memo M., Sigala S., Berruti A.
Cytotoxic effect of progesterone, tamoxifen and their combination in experimental cell models of human adrenocortical cancer.
Front. Endocrinol. 12:669426.1-669426.13(2021)

PubMed=35563746; DOI=10.3390/cells11091439; PMCID=PMC9103477
Sigala S., Bothou C., Penton D., Abate A., Peitzsch M., Cosentini D., Tiberio G.A.M., Bornstein S.R., Berruti A., Hantel C.
A comprehensive investigation of steroidogenic signaling in classical and new experimental cell models of adrenocortical carcinoma.
Cells 11:1439.1-1439.17(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049809
Entry history
Entry creation15-Dec-2022
Last entry update10-Apr-2025
Version number5