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Cellosaurus MUC-1 (CVCL_C4KG)

[Text version]
Cell line name MUC-1
Accession CVCL_C4KG
Resource Identification Initiative To cite this cell line use: MUC-1 (RRID:CVCL_C4KG)
Comments Characteristics: Established from a patient-derived xenograft also called MUC-1.
Omics: Genomics; Whole genome sequencing.
Derived from site: Metastatic; Neck, hypodermis; UBERON=UBERON_0000974+UBERON_0002072.
Sequence variations
Disease Adrenal cortex carcinoma (NCIt: C9325)
Adrenocortical carcinoma (ORDO: Orphanet_1501)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): PubMed=27764813

Markers:
AmelogeninX
CSF1PO12
D1S165615
D2S133826
D3S135816,18
D5S81811
D6S104312
D7S8208,10
D8S11798
D12S39119.3,22
D13S3179
D16S53911,14
D18S5114,18
D19S43313,14
D21S1129
FGA22,23.2
Penta D9
Penta E7,13
TH019.3
TPOX8
vWA16,17

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Publications

PubMed=27764813; DOI=10.18632/oncotarget.12685; PMCID=PMC5346714
Constanze Hantel, Igor Shapiro, Giada Poli, Costanza Chiapponi, Martin Bidlingmaier, Martin Reincke, Michaela Luconi, Sara Jung, Felix Beuschlein;
Targeting heterogeneity of adrenocortical carcinoma: evaluation and extension of preclinical tumor models to improve clinical translation.
Oncotarget 7:79292-79304(2016)

PubMed=33981288; DOI=10.3389/fendo.2021.669426; PMCID=PMC8108132
Elisa Rossini, Mariangela Tamburello, Andrea Abate, Silvia Beretta, Martina Fragni, Manuela Cominelli, Deborah Cosentini, Constanze Hantel, Federica Bono, Salvatore Grisanti, Pietro Luigi Poliani ...Show all 15 authors... , Guido Alberto Massimo Tiberio, Maurizio Memo, Sandra Sigala, Alfredo Berruti; Show fewer authors
Cytotoxic effect of progesterone, tamoxifen and their combination in experimental cell models of human adrenocortical cancer.
Front. Endocrinol. 12:669426.1-669426.13(2021)

PubMed=35563746; DOI=10.3390/cells11091439; PMCID=PMC9103477
Sandra Sigala, Christina Bothou, David Penton, Andrea Abate, Mirko Peitzsch, Deborah Cosentini, Guido Alberto Massimo Tiberio, Stefan Richard Bornstein, Alfredo Berruti, Constanze Hantel;
A comprehensive investigation of steroidogenic signaling in classical and new experimental cell models of adrenocortical carcinoma.
Cells 11:1439.1-1439.17(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049809
Entry history
Entry creation15-Dec-2022
Last entry update10-Apr-2025
Version number5