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Cellosaurus CuFi-4 (CVCL_C459)

[Text version]
Cell line name CuFi-4
Synonyms Cystic Fibrosis, University of Iowa-4
Accession CVCL_C459
Resource Identification Initiative To cite this cell line use: CuFi-4 (RRID:CVCL_C459)
Comments Karyotypic information: 48,XX,+5,+20 [10] (PubMed=12676769).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Sequence variations
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 33Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-4015

Markers:
AmelogeninX
CSF1PO13
D2S133820,23
D3S135814,18
D5S81811,13
D7S82010,12
D8S117911,14
D13S31711,12
D16S53912,13
D18S5114,15
D19S43314,15
D21S1129,30
FGA21,24
Penta D12
Penta E12,17
TH017
TPOX8,11
vWA17,18

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Publications

PubMed=12676769; DOI=10.1152/ajplung.00355.2002
Zabner J., Karp P., Seiler M., Phillips S.L., Mitchell C.J., Saavedra M.T., Welsh M., Klingelhutz A.J.
Development of cystic fibrosis and noncystic fibrosis airway cell lines.
Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L844-L854(2003)

Cross-references
Cell line collections (Providers) ATCC; CRL-4015
CancerTools; 154447
Biological sample resources BioSample; SAMN03471724
Encyclopedic resources Wikidata; Q54814857
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number26