ID   CuFi-4
AC   CVCL_C459
SY   Cystic Fibrosis, University of Iowa-4
DR   ATCC; CRL-4015
DR   BioSample; SAMN03471724
DR   CancerTools; 154447
DR   Wikidata; Q54814857
RX   PubMed=12676769;
CC   Karyotypic information: 48,XX,+5,+20 [10] (PubMed=12676769).
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=12676769).
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Gly551Asp (c.1652G>A); ClinVar=VCV000007120; Zygosity=Heterozygous (PubMed=12676769).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
ST   Source(s): ATCC=CRL-4015
ST   Amelogenin: X
ST   CSF1PO: 13
ST   D13S317: 11,12
ST   D16S539: 12,13
ST   D18S51: 14,15
ST   D19S433: 14,15
ST   D21S11: 29,30
ST   D2S1338: 20,23
ST   D3S1358: 14,18
ST   D5S818: 11,13
ST   D7S820: 10,12
ST   D8S1179: 11,14
ST   FGA: 21,24
ST   Penta D: 12
ST   Penta E: 12,17
ST   TH01: 7
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   33Y
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 26
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RX   PubMed=12676769; DOI=10.1152/ajplung.00355.2002;
RA   Zabner J., Karp P., Seiler M., Phillips S.L., Mitchell C.J.,
RA   Saavedra M.T., Welsh M., Klingelhutz A.J.;
RT   "Development of cystic fibrosis and noncystic fibrosis airway cell
RT   lines.";
RL   Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L844-L854(2003).
//