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Cellosaurus CP-D (CVCL_C454)

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Cell line name CP-D
Synonyms CP-D hTRT; CP-18821 hTERT
Accession CVCL_C454
Resource Identification Initiative To cite this cell line use: CP-D (RRID:CVCL_C454)
Comments Doubling time: ~39 hours (ATCC=CRL-4030).
Karyotypic information: Has lost chromosome Y.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Omics: Genomics; Whole genome sequencing.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Cell type: Epithelial cell of esophagus; CL=CL_0002252.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser303Alafs*42 (c.906del); Zygosity=Unspecified (from parent cell line).
Disease Barrett esophagus (NCIt: C2891)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8WD (CP-18821)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
STR profile Source(s): ATCC=CRL-4030

Markers:
AmelogeninX
CSF1PO12
D2S133823,25
D3S135815,16
D5S8189,12
D7S82010,11
D8S117911,15
D13S31712
D16S53910,13
D18S5113,16
D19S43315,15.2
D21S1129,32.2
FGA20,22
Penta D12,13
Penta E10
TH019,9.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=12807723; DOI=10.1093/carcin/bgg076; PMCID=PMC1559990
Maria Corinna A. Palanca-Wessels, Aloysius J. Klingelhutz, Brian J. Reid, Thomas H. Norwood, Kent E. Opheim, Thomas G. Paulson, Zi-Ding Feng, Peter S. Rabinovitch;
Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.
Carcinogenesis 24:1183-1190(2003)

PubMed=27594985; DOI=10.12688/f1000research.7033.1; PMCID=PMC4991527
Gianmarco Contino, Matthew D. Eldridge, Maria Secrier, Lawrence Bower, Rachael Fels Elliott, Jamie Weaver, Andy G. Lynch, Paul A.W. Edwards, Rebecca Clare Fitzgerald;
Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.
F1000Research 5:1336.1-1336.12(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-4030
Biological sample resources BioSample; SAMN03471733
Encyclopedic resources Wikidata; Q54814365
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number20