ID   CP-D
AC   CVCL_C454
SY   CP-D hTRT; CP-18821 hTERT
DR   ATCC; CRL-4030
DR   BioSample; SAMN03471733
DR   Wikidata; Q54814365
RX   PubMed=12807723;
RX   PubMed=27594985;
CC   Doubling time: ~39 hours (ATCC=CRL-4030).
CC   Karyotypic information: Has lost chromosome Y.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser303Alafs*42 (c.906del); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Omics: Genomics; Whole genome sequencing.
CC   Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
CC   Cell type: Epithelial cell of esophagus; CL=CL_0002252.
ST   Source(s): ATCC=CRL-4030
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 10,13
ST   D18S51: 13,16
ST   D19S433: 15,15.2
ST   D21S11: 29,32.2
ST   D2S1338: 23,25
ST   D3S1358: 15,16
ST   D5S818: 9,12
ST   D7S820: 10,11
ST   D8S1179: 11,15
ST   FGA: 20,22
ST   Penta D: 12,13
ST   Penta E: 10
ST   TH01: 9,9.3
ST   TPOX: 8
ST   vWA: 16
DI   NCIt; C2891; Barrett esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A8WD ! CP-18821
SX   Male
AG   Adult
CA   Telomerase immortalized cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 19
//
RX   PubMed=12807723; DOI=10.1093/carcin/bgg076; PMCID=PMC1559990;
RA   Palanca-Wessels M.C.A., Klingelhutz A.J., Reid B.J., Norwood T.H.,
RA   Opheim K.E., Paulson T.G., Feng Z.-D., Rabinovitch P.S.;
RT   "Extended lifespan of Barrett's esophagus epithelium transduced with
RT   the human telomerase catalytic subunit: a useful in vitro model.";
RL   Carcinogenesis 24:1183-1190(2003).
//
RX   PubMed=27594985; DOI=10.12688/f1000research.7033.1; PMCID=PMC4991527;
RA   Contino G., Eldridge M.D., Secrier M., Bower L., Elliott R.F., Weaver J.,
RA   Lynch A.G., Edwards P.A.W., Fitzgerald R.C.;
RT   "Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.";
RL   F1000Research 5:1336.1-1336.12(2016).
//