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Cellosaurus CP-B (CVCL_C452)

[Text version]
Cell line name CP-B
Synonyms CP-B hTRT; CP-52731 hTERT; ChTERT
Accession CVCL_C452
Resource Identification Initiative To cite this cell line use: CP-B (RRID:CVCL_C452)
Comments Doubling time: ~34 hours (ATCC=CRL-4028).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Cell type: Epithelial cell of esophagus; CL=CL_0002252.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Leu97Gln (c.290T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
Disease Barrett esophagus (NCIt: C2891)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8WE (CP-52731)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
STR profile Source(s): ATCC=CRL-4028

Markers:
AmelogeninX,Y
CSF1PO8,12
D2S133823,25
D3S135815,16
D5S81811,12
D7S82011,12
D8S117912,14
D13S3178,12
D16S53910,13
D18S5112,21
D19S43313,14
D21S1130
FGA22
Penta D13
Penta E17,19
TH018,9
TPOX8,9
vWA18,20

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Publications

PubMed=12807723; DOI=10.1093/carcin/bgg076; PMCID=PMC1559990
Palanca-Wessels M.C.A., Klingelhutz A.J., Reid B.J., Norwood T.H., Opheim K.E., Paulson T.G., Feng Z.-D., Rabinovitch P.S.
Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.
Carcinogenesis 24:1183-1190(2003)

Cross-references
Cell line collections (Providers) ATCC; CRL-4028
Biological sample resources BioSample; SAMN03471731
Encyclopedic resources Wikidata; Q54814363
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number15