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Cellosaurus PK15S10 (CVCL_C3VI)

[Text version]
Cell line name PK15S10
Synonyms PK15(S10); PK-15S10+; PK-15(S10+); PK-15 Siglec-10
Accession CVCL_C3VI
Resource Identification Initiative To cite this cell line use: PK15S10 (RRID:CVCL_C3VI)
Comments Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome (PRRSV).
Transfected with: UniProtKB; A0A068F110; Pig SIGLEC10.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Hampshire.
Hierarchy Parent: CVCL_2160 (PK-15)
CVCL_C3VJ (PK15S10-CD163)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=28742001; DOI=10.1099/jgv.0.000859
Xie J.-X., Christiaens I., Yang B., Breedam W.V., Cui T., Nauwynck H.J.
Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV).
J. Gen. Virol. 98:2030-2042(2017)

PubMed=30021620; DOI=10.1186/s13567-018-0569-z
Xie J.-X., Christiaens I., Yang B., Trus I., Devriendt B., Cui T.-T., Wei R.-F., Nauwynck H.J.
Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15(S1-CD163) and PK15(S10-CD163) cells.
Vet. Res. 49:67.1-67.13(2018)

Encyclopedic resources Wikidata; Q116050122
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3