Cellosaurus cell line 3.19.3 (CVCL

Cellosaurus 3.19.3 (CVCL_C3S6)

Cross-references
Cell line name	3.19.3
Accession	CVCL_C3S6
Resource Identification Initiative	To cite this cell line use: 3.19.3 (RRID:CVCL_C3S6)
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-7260. Monoclonal antibody isotype: IgG2, kappa. Monoclonal antibody target: UniProtKB; O15123; Human ANGPT2 (Note=Also reacts with mouse). Miscellaneous: As the immunized splenic B-cells are from Xenomouse mice the produced mAB is of human origin.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy	Parent: CVCL_4032 (P3X63Ag8.653)
Category	Hybridoma
Publications	PubMed=20053776; DOI=10.1158/1535-7163.MCT-09-0554 Jeffrey L. Brown, Z. Alexander Cao, Maria Pinzon-Ortiz, Jane Kendrew, Corinne Reimer, Sheng-Hua Wen, Joe Q. Zhou, Mohammad Tabrizi, Stephen Charles Emery, Brenda McDermott, Lourdes Pablo ...Show all 14 authors... , Patricia McCoon, Vahe Bedian, David Charles Blakey; Show fewer authors A human monoclonal anti-ANG2 antibody leads to broad antitumor activity in combination with VEGF inhibitors and chemotherapy agents in preclinical models. Mol. Cancer Ther. 9:145-156(2010) Patent=US10066011 Larry L. Green, Qing Zhou, Bruce A. Keyt, Xiao-Dong Yang, Stephen Charles Emery, David Charles Blakey; Antibodies directed to angiopoietin-2 and uses thereof. Patent number US10066011, 04-Sep-2018
Biological sample resources	ABCD; ABCD_AS321
Encyclopedic resources	Wikidata; Q116048090
Entry history
Entry creation	15-Dec-2022
Last entry update	02-May-2024
Version number	3