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Cellosaurus RAW-E6 (CVCL_C3NB)

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Cell line name RAW-E6
Accession CVCL_C3NB
Resource Identification Initiative To cite this cell line use: RAW-E6 (RRID:CVCL_C3NB)
Comments Characteristics: Expresses a EGFP-ESAT-6 fusion protein (PubMed=22117523).
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P9WNK7; Mycobacterium tuberculosis ESAT-6 (esxA).
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0493 (RAW 264.7)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=22117523
Hao Li, Ying Yin, Da-Yong Dong, Jun Zhang, Ling Fu, Chen-Guang Cai, Meng Wang, Jun-Jie Xu, Wei Chen;
Establishment of RAW264.7 cell line stably expressing Mycobacterium tuberculosis protein ESAT-6.
Sheng Wu Gong Cheng Xue Bao 27:1390-1396(2011)

PubMed=24341278
Ye Qu, Ying Yin, Hao Li, Ju Liu, Xiu-Xu Yang, Da-Yong Dong, Jun-Jie Xu, Wei Chen;
ESX-1 secreted protein ESAT-6 of Mycobacterium tuberculosis enhances the phagocytosis of RAW264.7 macrophages.
Wei Sheng Wu Xue Bao 53:860-866(2013)

Cross-references
Encyclopedic resources Wikidata; Q116050159
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number6