Cellosaurus 409B2 HCN4-EGFP/SHOX2-mCherry (CVCL_C3LU)
| Cell line name | 409B2 HCN4-EGFP/SHOX2-mCherry |
|---|---|
| Accession | CVCL_C3LU |
| Resource Identification Initiative | To cite this cell line use: 409B2 HCN4-EGFP/SHOX2-mCherry (RRID:CVCL_C3LU) |
| Comments | Population: Caucasian. Characteristics: Dual reporter cell line. Using homologous recombination EGFP was inserted at the N-terminus of HCN4 and using CRISPR/Cas9 mCherry was inserted at the N-terminus of SHOX2 (PubMed=36092505). Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)). Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_K092 (409B2) |
| Sex of cell | Female |
| Age at sampling | 36Y |
| Category | Induced pluripotent stem cell |
| Publications | PubMed=36092505; DOI=10.1016/j.reth.2022.07.012; PMCID=PMC9420958 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q116048197 |
| Entry history | |
| Entry creation | 15-Dec-2022 |
| Last entry update | 10-Sep-2024 |
| Version number | 4 |