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Cellosaurus 409B2 HCN4-EGFP/SHOX2-mCherry (CVCL_C3LU)

[Text version]
Cell line name 409B2 HCN4-EGFP/SHOX2-mCherry
Accession CVCL_C3LU
Resource Identification Initiative To cite this cell line use: 409B2 HCN4-EGFP/SHOX2-mCherry (RRID:CVCL_C3LU)
Comments Population: Caucasian.
Characteristics: Dual reporter cell line. Using homologous recombination EGFP was inserted at the N-terminus of HCN4 and using CRISPR/Cas9 mCherry was inserted at the N-terminus of SHOX2 (PubMed=36092505).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_K092 (409B2)
Sex of cell Female
Age at sampling 36Y
Category Induced pluripotent stem cell
Publications

PubMed=36092505; DOI=10.1016/j.reth.2022.07.012
Wakimizu T., Morikawa K., Fukumura K., Yuki T., Adachi T., Kurata Y., Miake J., Hisatome I., Tsuneto M., Shirayoshi Y.
SHOX2 refines the identification of human sinoatrial nodal cell population in the in vitro cardiac differentiation.
Regen. Ther. 21:239-249(2022)

Cross-references
Encyclopedic resources Wikidata; Q116048197
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3