Cellosaurus cell line 92-2 [Human uveal melanoma] (CVCL

Cellosaurus 92-2 [Human uveal melanoma] (CVCL_C300)

Cross-references
Cell line name	92-2 [Human uveal melanoma]
Synonyms	92_2; 92.2
Accession	CVCL_C300
Resource Identification Initiative	To cite this cell line use: 92-2 [Human uveal melanoma] (RRID:CVCL_C300)
Comments	Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations	Mutation; HGNC; HGNC:4390; GNAQ; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000375955; Zygosity=Heterozygous (PubMed=22383533).
Disease	Uveal melanoma (NCIt: C7712) Uveal melanoma (ORDO: Orphanet_39044)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_8607 ! 92-1 [Human uveal melanoma]
Sex of cell	Female
Age at sampling	76Y
Category	Cancer cell line
Publications	PubMed=7622289; DOI=10.1002/ijc.2910620208 Itte De Waard-Siebinga, Derk-Jan R. Blom, Marieke Griffioen, Peter I. Schrier, Ed Hoogendoorn, Geoffrey C. Beverstock, Erik H.J. Danen, Martine Johanna Jager; Establishment and characterization of an uveal-melanoma cell line. Int. J. Cancer 62:155-161(1995) PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676 Ken Dutton-Regester, Darryl Irwin, Priscilla Hunt, Lauren G. Aoude, Varsha Tembe, Gulietta M. Pupo, Cathy Lanagan, Candace D. Carter, Linda O'Connor, Michael O'Rourke, Richard Anthony Scolyer ...Show all 15 authors... , Graham J. Mann, Christopher W. Schmidt, Adrian Herington, Nicholas K. Hayward; Show fewer authors A high-throughput panel for identifying clinically relevant mutation profiles in melanoma. Mol. Cancer Ther. 11:888-897(2012)
Cell line databases/resources	cancercelllines; CVCL_C300
Encyclopedic resources	Wikidata; Q54605665
Polymorphism and mutation databases	Cosmic; 916138
Entry history
Entry creation	22-Oct-2012
Last entry update	10-Apr-2025
Version number	15