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Cellosaurus 50B11 clone D4W (CVCL_C1LC)

[Text version]
Cell line name 50B11 clone D4W
Accession CVCL_C1LC
Resource Identification Initiative To cite this cell line use: 50B11 clone D4W (RRID:CVCL_C1LC)
Comments Knockout cell: Method=CRISPR/Cas9; RGD; 1589721; Gla.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Dorsal root ganglion; UBERON=UBERON_0000044.
Cell type: Neuron; CL=CL_0000540.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Hierarchy Parent: CVCL_M745 (50B11)
Sex of cell Sex unspecified
Age at sampling 14-15FD
Category Transformed cell line
Publications

PubMed=35782611; DOI=10.1016/j.ymgmr.2022.100871; PMCID=PMC9248215
Kaneski C.R., Hanover J.A., Schueler Hoffman U.H.
Generation of an in vitro model for peripheral neuropathy in Fabry disease using CRISPR-Cas9 in the nociceptive dorsal root ganglion cell line 50B11.
Mol. Genet. Metab. Rep. 31:100871.1-100871.8(2022)

Cross-references
Encyclopedic resources Wikidata; Q114310451
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number8