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Cellosaurus GM847/hTERT-3 (CVCL_C1HE)

[Text version]
Cell line name GM847/hTERT-3
Accession CVCL_C1HE
Resource Identification Initiative To cite this cell line use: GM847/hTERT-3 (RRID:CVCL_C1HE)
Comments Population: African American.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Lesch-Nyhan syndrome (NCIt: C61255)
Lesch-Nyhan syndrome (ORDO: Orphanet_510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7908 (GM00847)
Children:
CVCL_C1HG (GM847/hTERT-3 subclone 9)
Sex of cell Male
Age at sampling 5Y6M
Category Transformed cell line
Publications

PubMed=11359895; DOI=10.1128/mcb.21.12.3862-3875.2001; PMCID=PMC87050
Kilian Perrem, Lorel M. Colgin, Axel A. Neumann, Thomas R. Yeager, Roger Robert Reddel;
Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells.
Mol. Cell. Biol. 21:3862-3875(2001)

PubMed=19935656; DOI=10.1038/nbt.1587
Jeremy David Henson, Ying Cao, Lily I. Huschtscha, Andy C.-M. Chang, Amy Y.M. Au, Hilda A. Pickett, Roger Robert Reddel;
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
Nat. Biotechnol. 27:1181-1185(2009)

Cross-references
Encyclopedic resources Wikidata; Q114311535
Entry history
Entry creation22-Sep-2022
Last entry update14-Aug-2025
Version number7