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Cellosaurus 585A1-C7 #3-3 (CVCL_C1G0)

[Text version]
Cell line name 585A1-C7 #3-3
Synonyms 585A1-C7-retained #3-3; C7 #3-3
Accession CVCL_C1G0
Resource Identification Initiative To cite this cell line use: 585A1-C7 #3-3 (RRID:CVCL_C1G0)
Comments Population: Japanese.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4931; HLA-A.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4932; HLA-B.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4933; HLA-C (Note=1 of 2 alleles: C*12:02, leaving C*07:01 intact).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DQ06 (585A1)
Sex of cell Male
Age at sampling 30-39Y
Category Induced pluripotent stem cell
Publications

PubMed=30853558; DOI=10.1016/j.stem.2019.02.005
Xu H.-G., Wang B., Ono M., Kagita A., Fujii K., Sasakawa N., Ueda T., Gee P., Nishikawa M., Nomura M., Kitaoka F., Takahashi T., Okita K., Yoshida Y., Kaneko S., Hotta A.
Targeted disruption of HLA genes via CRISPR-Cas9 generates iPSCs with enhanced immune compatibility.
Cell Stem Cell 24:566-578.e7(2019)

Patent=US20200407693
Hotta A., Xu H.-G., Kaneko S., Wang B.
Method for producing low-antigenic cell.
Patent number US20200407693, 31-Dec-2020

Cross-references
Encyclopedic resources Wikidata; Q114310461
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number6