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Cellosaurus RPTEC_MSH6_543 (CVCL_C1C1)

[Text version]
Cell line name RPTEC_MSH6_543
Accession CVCL_C1C1
Resource Identification Initiative To cite this cell line use: RPTEC_MSH6_543 (RRID:CVCL_C1C1)
Comments Part of: Cancer Pathway Knockout Panel.
Knockout cell: Method=CRISPR/Cas9; HGNC; 7329; MSH6.
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
Cell type: Epithelial cell of proximal tubule; CL=CL_0002306.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_K278 (RPTEC/TERT1)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
Publications

PubMed=35692635; DOI=10.1016/j.isci.2022.104437
Cook A.L., Wyhs N., Sur S., Ptak B., Popoli M., Dobbyn L., Papadopoulos T., Bettegowda C., Papadopoulos N., Vogelstein B., Zhou S., Kinzler K.W.
An isogenic cell line panel for sequence-based screening of targeted anticancer drugs.
IScience 25:104437.1-104437.14(2022)

Cross-references
Encyclopedic resources Wikidata; Q114312912
Entry history
Entry creation22-Sep-2022
Last entry update29-Jun-2023
Version number4