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Cellosaurus PCI-03 (CVCL_C169)

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Cell line name PCI-03
Synonyms PCI-3
Accession CVCL_C169
Resource Identification Initiative To cite this cell line use: PCI-03 (RRID:CVCL_C169)
Comments Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=21868764). Originally thought to originate from a 50 year old male patient with a retromolar trigone squamous cell carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00420.
Population: Caucasian.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO11
D5S81813
D7S8208,11
D13S31711
D16S53911
TH017
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=2766286
Dae Seog Heo, Carl Henry Snyderman, Susanne M. Gollin, Shao-Ming Pan, Emily Walker, Ranjan Deka, E. Leon Barnes, Jonas T. Johnson, Ronald Bruce Herberman, Theresa L. Whiteside;
Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines.
Cancer Res. 49:5167-5175(1989)

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks ...Show all 15 authors... , Jennifer Rubin Grandis, David Sidransky, Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C169
Biological sample resources BioSample; SAMN03151894
Encyclopedic resources Wikidata; Q54938648
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number26