ID   PCI-03
AC   CVCL_C169
SY   PCI-3
DR   BioSample; SAMN03151894
DR   cancercelllines; CVCL_C169
DR   Wikidata; Q54938648
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RX   PubMed=2766286;
RX   PubMed=17312569;
RX   PubMed=21868764;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=21868764). Originally thought to originate from a 50 year old male patient with a retromolar trigone squamous cell carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00420.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
ST   Source(s): PubMed=21868764
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 11
ST   D5S818: 13
ST   D7S820: 8,11
ST   TH01: 7
ST   TPOX: 8,9
ST   vWA: 17
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0035 ! PC-3
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 26
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RX   PubMed=2766286;
RA   Heo, Dae Seog
RA   Snyderman, Carl Henry
RA   Gollin, Susanne M.
RA   Pan, Shao-Ming
RA   Walker, Emily
RA   Deka, Ranjan
RA   Barnes, E. Leon
RA   Johnson, Jonas T.
RA   Herberman, Ronald Bruce
RA   Whiteside, Theresa L.
RT   "Biology, cytogenetics, and sensitivity to immunological effector
RT   cells of new head and neck squamous cell carcinoma lines.";
RL   Cancer Res. 49:5167-5175(1989).
//
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662;
RA   Zhao, Mei
RA   Sano, Daisuke
RA   Pickering, Curtis R.
RA   Jasser, Samar A.
RA   Henderson, Ying C.
RA   Clayman, Gary L.
RA   Sturgis, Erich M.
RA   Ow, Thomas J.
RA   Lotan, Reuben
RA   Carey, Thomas E.
RA   Sacks, Peter G.
RA   Grandis, Jennifer Rubin
RA   Sidransky, David
RA   Heldin, Nils-Erik
RA   Myers, Jeffrey N.
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin, Charles J.
RA   Grandis, Jennifer Rubin
RA   Carey, Thomas E.
RA   Gollin, Susanne M.
RA   Whiteside, Theresa L.
RA   Koch, Wayne M.
RA   Ferris, Robert Louis
RA   Lai, Stephen Y.
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RA   Carey, Thomas E.
RT   "Head and neck tumor cell lines.";
RL   (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994).
//