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Cellosaurus BL-74 (CVCL_C158)

[Text version]
Cell line name BL-74
Synonyms BL74; BL 74; BL 074; IARC/BL74; IARC/BL 74; IARC-BL74; IARC BL74; IARC BL 74
Accession CVCL_C158
Resource Identification Initiative To cite this cell line use: BL-74 (RRID:CVCL_C158)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Caucasian.
Doubling time: ~45 hours (DSMZ=ACC-922).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C9BR ! IARC-290A
CVCL_IV08 ! IARC-290B
Sex of cell Female
Age at sampling 33Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-922

Markers:
AmelogeninX
CSF1PO10
D2S133817,24
D3S135815,17
D5S81811,12
D7S8208,10
D8S117912,13
D13S31712,14
D16S5398,13
D18S5112,15
D19S43313,17
D21S1130,32.2
FGA21
Penta D12,13
Penta E13,16
TH017
TPOX10,11
vWA19,20

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Publications

PubMed=2985508; DOI=10.1002/ijc.2910350404
Rowe M., Rooney C.M., Rickinson A.B., Lenoir G.M., Rupani H., Moss D.J., Stein H., Epstein M.A.
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=3934070
Lenoir G.M., Vuillaume M., Bonnardel C.
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M., Manel A.-M., Vincent C., Bryon P.-A.
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677
Gregory C.D., Murray R.J., Edwards C.F., Rickinson A.B.
Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.
J. Exp. Med. 167:1811-1824(1988)

PubMed=1356511; DOI=10.1182/blood.V80.7.1781.1781
Gaidano G., Hauptschein R.S., Parsa N.Z., Offit K., Rao P.H., Lenoir G.M., Knowles D.M., Chaganti R.S.K., Dalla-Favera R.
Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma.
Blood 80:1781-1787(1992)

PubMed=10997876; DOI=10.1093/dnares/7.4.261
Hauptschein R.S., Gaidano G., Rao P.H., Scotto L., Edwards Y.H., Chaganti R.S.K., Dalla-Favera R.
An apparent interlocus gene conversion-like event at a putative tumor suppressor gene locus on human chromosome 6q27 in a Burkitt's lymphoma cell line.
DNA Res. 7:261-272(2000)

PubMed=11793449; DOI=10.1002/gcc.10022
Sobol H., Benziane A., Kerangueven F., Yin L., Noguchi T., Pauly S., Eisinger F., Longy M., Romeo G., Lenoir G.M., Birnbaum D.
Genome-wide search for loss of heterozygosity in Burkitt lymphoma cell lines.
Genes Chromosomes Cancer 33:217-224(2002)

Cross-references
Cell line collections (Providers) DSMZ; ACC-922
Cell line databases/resources DSMZCellDive; ACC-922
Encyclopedic resources Wikidata; Q54797250
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number16