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Cellosaurus BL-74 (CVCL_C158)

[Text version]
Cell line name BL-74
Synonyms BL74; BL 74; BL 074; IARC/BL74; IARC/BL 74; IARC-BL74; IARC BL74; IARC BL 74
Accession CVCL_C158
Resource Identification Initiative To cite this cell line use: BL-74 (RRID:CVCL_C158)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Caucasian.
Doubling time: ~45 hours (DSMZ=ACC-922).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C9BR ! IARC-290A
CVCL_IV08 ! IARC-290B
Sex of cell Female
Age at sampling 33Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-922

Markers:
AmelogeninX
CSF1PO10
D2S133817,24
D3S135815,17
D5S81811,12
D7S8208,10
D8S117912,13
D13S31712,14
D16S5398,13
D18S5112,15
D19S43313,17
D21S1130,32.2
FGA21
Penta D12,13
Penta E13,16
TH017
TPOX10,11
vWA19,20

Run an STR similarity search on this cell line
Publications

PubMed=2985508; DOI=10.1002/ijc.2910350404
Martin Rowe, Cliona M. Rooney, Alan Bernard Rickinson, Gilbert Marcel Lenoir, Hitesh Rupani, Denis J. Moss, Harald Stein, Michael Anthony Epstein;
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=3934070
Gilbert Marcel Lenoir, Michele Vuillaume, Colette Bonnardel;
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Jacques H.M. Cohen, Jean-Pierre Revillard, Jean-Pierre Magaud, Gilbert Marcel Lenoir, Michele Vuillaume, Anne-Marie Manel, Claude Vincent, Paul-Andre Bryon;
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677
Christopher D. Gregory, Ruth J. Murray, Carole F. Edwards, Alan Bernard Rickinson;
Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.
J. Exp. Med. 167:1811-1824(1988)

PubMed=1356511; DOI=10.1182/blood.V80.7.1781.1781
Gianluca Gaidano, Robert S. Hauptschein, Nasser Z. Parsa, Kenneth Offit, Pulivarthi H. Rao, Gilbert Marcel Lenoir, Daniel M. Knowles, Raju S.K. Chaganti, Riccardo Dalla-Favera;
Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma.
Blood 80:1781-1787(1992)

PubMed=10997876; DOI=10.1093/dnares/7.4.261
Robert S. Hauptschein, Gianluca Gaidano, Pulivarthi H. Rao, Luigi Scotto, Yvonne H. Edwards, Raju S.K. Chaganti, Riccardo Dalla-Favera;
An apparent interlocus gene conversion-like event at a putative tumor suppressor gene locus on human chromosome 6q27 in a Burkitt's lymphoma cell line.
DNA Res. 7:261-272(2000)

PubMed=11793449; DOI=10.1002/gcc.10022
Hagay Sobol, Athmane Benziane, Fabienne Kerangueven, Luo Yin, Tetsuro Noguchi, Suzanne Pauly, Francois Eisinger, Michel Longy, Giovanni Romeo, Gilbert Marcel Lenoir, Daniel Birnbaum;
Genome-wide search for loss of heterozygosity in Burkitt lymphoma cell lines.
Genes Chromosomes Cancer 33:217-224(2002)

Cross-references
Cell line collections (Providers) DSMZ; ACC-922
Cell line databases/resources DSMZCellDive; ACC-922
Encyclopedic resources Wikidata; Q54797250
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number16