ID   BL-74
AC   CVCL_C158
SY   BL74; BL 74; BL 074; IARC/BL74; IARC/BL 74; IARC-BL74; IARC BL74; IARC BL 74
DR   DSMZ; ACC-922
DR   DSMZCellDive; ACC-922
DR   Wikidata; Q54797250
RX   PubMed=1356511;
RX   PubMed=2898508;
RX   PubMed=2985508;
RX   PubMed=3027441;
RX   PubMed=3934070;
RX   PubMed=10997876;
RX   PubMed=11793449;
CC   From: International Agency of Research on Cancer (IARC); Lyon; France.
CC   Population: Caucasian.
CC   Doubling time: ~45 hours (DSMZ=ACC-922).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): DSMZ=ACC-922
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 12,14
ST   D16S539: 8,13
ST   D18S51: 12,15
ST   D19S433: 13,17
ST   D21S11: 30,32.2
ST   D2S1338: 17,24
ST   D3S1358: 15,17
ST   D5S818: 11,12
ST   D7S820: 8,10
ST   D8S1179: 12,13
ST   FGA: 21
ST   Penta D: 12,13
ST   Penta E: 13,16
ST   TH01: 7
ST   TPOX: 10,11
ST   vWA: 19,20
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C9BR ! IARC-290A
OI   CVCL_IV08 ! IARC-290B
SX   Female
AG   33Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-09-24; Version: 16
//
RX   PubMed=1356511; DOI=10.1182/blood.V80.7.1781.1781;
RA   Gaidano G., Hauptschein R.S., Parsa N.Z., Offit K., Rao P.H.,
RA   Lenoir G.M., Knowles D.M., Chaganti R.S.K., Dalla-Favera R.;
RT   "Deletions involving two distinct regions of 6q in B-cell non-Hodgkin
RT   lymphoma.";
RL   Blood 80:1781-1787(1992).
//
RX   PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677;
RA   Gregory C.D., Murray R.J., Edwards C.F., Rickinson A.B.;
RT   "Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in
RT   Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell
RT   escape from virus-specific T cell surveillance.";
RL   J. Exp. Med. 167:1811-1824(1988).
//
RX   PubMed=2985508; DOI=10.1002/ijc.2910350404;
RA   Rowe M., Rooney C.M., Rickinson A.B., Lenoir G.M., Rupani H.,
RA   Moss D.J., Stein H., Epstein M.A.;
RT   "Distinctions between endemic and sporadic forms of Epstein-Barr
RT   virus-positive Burkitt's lymphoma.";
RL   Int. J. Cancer 35:435-441(1985).
//
RX   PubMed=3027441; DOI=10.1093/jnci/78.2.235;
RA   Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M.,
RA   Manel A.-M., Vincent C., Bryon P.-A.;
RT   "B-cell maturation stages of Burkitt's lymphoma cell lines according
RT   to Epstein-Barr virus status and type of chromosome translocation.";
RL   J. Natl. Cancer Inst. 78:235-242(1987).
//
RX   PubMed=3934070;
RA   Lenoir G.M., Vuillaume M., Bonnardel C.;
RT   "The use of lymphomatous and lymphoblastoid cell lines in the study of
RT   Burkitt's lymphoma.";
RL   IARC Sci. Publ. 60:309-318(1985).
//
RX   PubMed=10997876; DOI=10.1093/dnares/7.4.261;
RA   Hauptschein R.S., Gaidano G., Rao P.H., Scotto L., Edwards Y.H.,
RA   Chaganti R.S.K., Dalla-Favera R.;
RT   "An apparent interlocus gene conversion-like event at a putative tumor
RT   suppressor gene locus on human chromosome 6q27 in a Burkitt's
RT   lymphoma cell line.";
RL   DNA Res. 7:261-272(2000).
//
RX   PubMed=11793449; DOI=10.1002/gcc.10022;
RA   Sobol H., Benziane A., Kerangueven F., Yin L., Noguchi T., Pauly S.,
RA   Eisinger F., Longy M., Romeo G., Lenoir G.M., Birnbaum D.;
RT   "Genome-wide search for loss of heterozygosity in Burkitt lymphoma
RT   cell lines.";
RL   Genes Chromosomes Cancer 33:217-224(2002).
//