Cellosaurus ACTOne TSHR (CVCL_C0TU)
| Cell line name | ACTOne TSHR |
|---|---|
| Accession | CVCL_C0TU |
| Resource Identification Initiative | To cite this cell line use: ACTOne TSHR (RRID:CVCL_C0TU) |
| Comments | Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions). Transfected with: RGD; 2367; Cnga2 (with p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC). Transfected with: HGNC; 12373; TSHR. Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C0RU (HEK293-CNG) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | http://www.codexbiosolutions.com/wp-content/uploads/cb-80200-242.pdf |
| Publications | PubMed=18216391; DOI=10.1177/1087057107313786 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112929196 |
| Entry history | |
| Entry creation | 23-Jun-2022 |
| Last entry update | 29-Jun-2023 |
| Version number | 4 |