Cellosaurus ACTOne PDE1C (CVCL_C0TH)
| Cell line name | ACTOne PDE1C |
|---|---|
| Accession | CVCL_C0TH |
| Resource Identification Initiative | To cite this cell line use: ACTOne PDE1C (RRID:CVCL_C0TH) |
| Comments | Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions). Characteristics: Expresses a constitutively active over-expressed Gs-coupled GPCR. Transfected with: RGD; 2367; Cnga2 (with p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC). Transfected with: HGNC; 8776; PDE1C. Transfected with: UniProtKB; P33967; B.cereus Bsr. Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C0RW (HEK293-CNG-Gs) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | http://www.codexbiosolutions.com/wp-content/uploads/cb-81200-104.pdf |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112929183 |
| Entry history | |
| Entry creation | 23-Jun-2022 |
| Last entry update | 05-Oct-2023 |
| Version number | 5 |