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Cellosaurus PC12-FR (CVCL_C0PX)

[Text version]
Cell line name PC12-FR
Synonyms PC12-Fast Responding; PC12-251; PC12 clone 251
Accession CVCL_C0PX
Resource Identification Initiative To cite this cell line use: PC12-FR (RRID:CVCL_C0PX)
Comments Characteristics: Established after 3 passages by subcutaneous injection of the parent cell line into Deaconess rats.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Rat adrenal gland pheochromocytoma (NCIt: C121568)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH.
Hierarchy Parent: CVCL_0481 (PC12)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line

PubMed=6303817; DOI=10.1016/S0014-4827(83)80019-6
Heumann R., Kachel V., Thoenen H.
Relationship between NGF-mediated volume increase and 'priming effect' in fast and slow reacting clones of PC12 pheochromocytoma cells. Role of cAMP.
Exp. Cell Res. 145:179-190(1983)

PubMed=6577005; DOI=10.1016/S0021-9258(17)44421-8
Lee R.W.H., Huttner W.B.
Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase.
J. Biol. Chem. 258:11326-11334(1983)

PubMed=8900203; DOI=10.1074/jbc.271.43.27116
Corradi N., Borgonovo B., Clementi E., Bassetti M., Racchetti G., Consalez G.G., Huttner W.B., Meldolesi J., Rosa P.
Overall lack of regulated secretion in a PC12 variant cell clone.
J. Biol. Chem. 271:27116-27124(1996)

PubMed=9856988; DOI=10.1074/jbc.273.52.34683
Borgonovo B., Racchetti G., Malosio M.L., Benfante R., Podini P., Rosa P., Meldolesi J.
Neurosecretion competence, an independently regulated trait of the neurosecretory cell phenotype.
J. Biol. Chem. 273:34683-34686(1998)

Encyclopedic resources Wikidata; Q112930281
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number5