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Cellosaurus PC12-27 c7 (CVCL_C0PW)

[Text version]
Cell line name PC12-27 c7
Synonyms PC12 clone 27 subclone c7
Accession CVCL_C0PW
Resource Identification Initiative To cite this cell line use: PC12-27 c7 (RRID:CVCL_C0PW)
Comments Characteristics: Neurosecretion incompetent (from parent cell line).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1930; CHGB.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Rat adrenal gland pheochromocytoma (NCIt: C121568)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy Parent: CVCL_C0PV (PC12-27)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8900203; DOI=10.1074/jbc.271.43.27116
Corradi N., Borgonovo B., Clementi E., Bassetti M., Racchetti G., Consalez G.G., Huttner W.B., Meldolesi J., Rosa P.
Overall lack of regulated secretion in a PC12 variant cell clone.
J. Biol. Chem. 271:27116-27124(1996)

PubMed=9856988; DOI=10.1074/jbc.273.52.34683
Borgonovo B., Racchetti G., Malosio M.L., Benfante R., Podini P., Rosa P., Meldolesi J.
Neurosecretion competence, an independently regulated trait of the neurosecretory cell phenotype.
J. Biol. Chem. 273:34683-34686(1998)

Cross-references
Encyclopedic resources Wikidata; Q112930278
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number9