Cellosaurus cell line PC12-21 (CVCL

Cellosaurus PC12-21 (CVCL_C0PU)

Cross-references
Cell line name	PC12-21
Synonyms	PC12 clone 21
Accession	CVCL_C0PU
Resource Identification Initiative	To cite this cell line use: PC12-21 (RRID:CVCL_C0PU)
Comments	Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease	Rat adrenal gland pheochromocytoma (NCIt: C121568)
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy	Parent: CVCL_0481 (PC12)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=1657914; DOI=10.1016/S0021-9258(18)54903-6 Daniele Zacchetti, Emilio Clementi, Cristina Fasolato, Paola Lorenzon, Michela Zottini, Fabio Grohovaz, Guido Fumagalli, Tullio Pozzan, Jacopo Meldolesi; Intracellular Ca2+ pools in PC12 cells. A unique, rapidly exchanging pool is sensitive to both inositol 1,4,5-trisphosphate and caffeine-ryanodine. J. Biol. Chem. 266:20152-20158(1991) PubMed=12106430; DOI=10.1111/j.1460-9568.1992.tb00121.x Emilio Clementi, Gabriella Racchetti, Daniele Zacchetti, Maria Carla Panzeri, Jacopo Meldolesi; Differential expression of markers and activities in a group of PC12 nerve cell clones. Eur. J. Neurosci. 4:944-953(1992) PubMed=9933147; DOI=10.1007/PL00005319 Giulia Arslan, Bjorn Kull, Bertil B. Fredholm; Signaling via A2A adenosine receptor in four PC12 cell clones. Naunyn Schmiedebergs Arch. Pharmacol. 359:28-32(1999)
Encyclopedic resources	Wikidata; Q112930275
Entry history
Entry creation	23-Jun-2022
Last entry update	14-Aug-2025
Version number	8