Cellosaurus NSI002-B (CVCL_C0HP)
| Cell line name | NSI002-B |
|---|---|
| Synonyms | AAVS1-EGFP-Di |
| Accession | CVCL_C0HP |
| Resource Identification Initiative | To cite this cell line use: NSI002-B (RRID:CVCL_C0HP) |
| Comments | From: Stem Cell and Neurobiology Lab, National Centre for Cell Science; Pune; India. Population: Caucasian. Characteristics: Using ZFN a PuroR-CAG-EGFP cassette was introduced in the AAVS1 safe harbor locus (PubMed=35961104). Karyotypic information: Lost the third copy of chromosome 21 (from parent cell line). Genetic integration: Method=ZFN; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=ZFN; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Chest, skin; UBERON=UBERON_0001868. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Disease | Down syndrome (NCIt: C2993) Down syndrome (ORDO: Orphanet_870) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C1XZ (DS1-iPS4-Disomic) |
| Sex of cell | Male |
| Age at sampling | 1Y |
| Category | Induced pluripotent stem cell |
| Publications | PubMed=35961104; DOI=10.1016/j.scr.2022.102890 |
| Cross-references | |
| Cell line databases/resources | hPSCreg; NSI002-B |
| Encyclopedic resources | Wikidata; Q112930237 |
| Entry history | |
| Entry creation | 23-Jun-2022 |
| Last entry update | 14-Aug-2025 |
| Version number | 7 |