ID   NSI002-B
AC   CVCL_C0HP
SY   AAVS1-EGFP-Di
DR   hPSCreg; NSI002-B
DR   Wikidata; Q112930237
RX   PubMed=35961104;
CC   From: Stem Cell and Neurobiology Lab, National Centre for Cell Science; Pune; India.
CC   Population: Caucasian.
CC   Characteristics: Using ZFN a PuroR-CAG-EGFP cassette was introduced in the AAVS1 safe harbor locus (PubMed=35961104).
CC   Karyotypic information: Lost the third copy of chromosome 21 (from parent cell line).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Chest, skin; UBERON=UBERON_0001868.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C2993; Down syndrome
DI   ORDO; Orphanet_870; Down syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C1XZ ! DS1-iPS4-Disomic
SX   Male
AG   1Y
CA   Induced pluripotent stem cell
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 5
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RX   PubMed=35961104; DOI=10.1016/j.scr.2022.102890;
RA   Sharma V., Nehra S., Singhal N.;
RT   "Generation of AAVS1-EGFP reporter cell lines from an isogenic pair of
RT   trisomy 21 and euploid human iPSCs.";
RL   Stem Cell Res. 64:102890-102890(2022).
//