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Cellosaurus SUSMi005-A-5.1 (CVCL_C0H0)

[Text version]
Cell line name SUSMi005-A-5.1
Synonyms SNCA3X 4KO C1
Accession CVCL_C0H0
Resource Identification Initiative To cite this cell line use: SUSMi005-A-5.1 (RRID:CVCL_C0H0)
Comments From: Stanford University School of Medicine; Stanford; USA.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9 (4 of 4 alleles); HGNC; 11138; SNCA.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Gene amplification; HGNC; 11138; SNCA; Triplication; Zygosity=Unspecified (from parent cell line).
Disease Parkinson disease 4, autosomal dominant (NCIt: C198604)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A4QV (Trpl17)
Sex of cell Male
Age at sampling 48Y
Category Induced pluripotent stem cell

PubMed=35263701; DOI=10.1016/j.scr.2022.102733
Zafar F., Nallur Srinivasaraghavan V., Chen M.Y., Morato Torres C.A., Schule B.
Isogenic human SNCA gene dosage induced pluripotent stem cells to model Parkinson's disease.
Stem Cell Res. 60:102733-102733(2022)

Cell line databases/resources hPSCreg; SUSMi005-A-5
Biological sample resources BioSamples; SAMEA12312969
Encyclopedic resources Wikidata; Q112930443
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number4