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Cellosaurus Abcam Caco-2 TMPRSS2 KO (CVCL_C0BM)

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Cell line name Abcam Caco-2 TMPRSS2 KO
Synonyms Human TMPRSS2 knockout Caco-2
Accession CVCL_C0BM
Resource Identification Initiative To cite this cell line use: Abcam Caco-2 TMPRSS2 KO (RRID:CVCL_C0BM)
Comments Group: SARS-CoV-2 research cell line.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11876; TMPRSS2.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Gln1367Ter (c.4099C>T); ClinVar=VCV000376060; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly245Ala (c.734G>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Asp351His (c.1051G>C); ClinVar=VCV000375998; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu204Ter (c.610G>T); ClinVar=VCV000977783; Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0025 (Caco-2)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Cell line collections (Providers) Abcam; ab273737
Cell line databases/resources cancercelllines; CVCL_C0BM
Encyclopedic resources Wikidata; Q112927716
Entry history
Entry creation23-Jun-2022
Last entry update30-Jan-2024
Version number6