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Cellosaurus Abcam LNCaP clone FGC TMPRSS2 KO (CVCL_C0BI)

[Text version]
Cell line name Abcam LNCaP clone FGC TMPRSS2 KO
Synonyms Human TMPRSS2 knockout LNCaP
Accession CVCL_C0BI
Resource Identification Initiative To cite this cell line use: Abcam LNCaP clone FGC TMPRSS2 KO (RRID:CVCL_C0BI)
Comments Group: SARS-CoV-2 research cell line.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11876; TMPRSS2.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1379 (LNCaP clone FGC)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Abcam; ab273745
Cell line databases/resources cancercelllines; CVCL_C0BI
Encyclopedic resources Wikidata; Q112928360
Entry history
Entry creation23-Jun-2022
Last entry update30-Jan-2024
Version number6