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Cellosaurus UPCI-SCC-036 (CVCL_C030)

[Text version]
Cell line name UPCI-SCC-036
Synonyms UPCI:SCC036; SCC036
Accession CVCL_C030
Resource Identification Initiative To cite this cell line use: UPCI-SCC-036 (RRID:CVCL_C030)
Comments Population: Caucasian.
Virology: The tumor is positive to HPV (PubMed=17112776), but the cell line is HPV negative (PubMed=23419152; PubMed=24403267).
Doubling time: ~48 hours (DSMZ=ACC-865).
Omics: DNA methylation analysis.
Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
Sequence variations
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C050 ! UPCI-SCC-104
CVCL_C056 ! UPCI-SCC-142
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-865

Markers:
AmelogeninX
CSF1PO11
D2S133822,25
D3S135818
D5S81811,12
D7S8209,10
D8S117913,14
D13S31711,13
D16S53911,12
D18S5117
D19S43313
D21S1129,30
FGA20
Penta D9
Penta E11
TH016,9
TPOX11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=12872257; DOI=10.1002/humu.10248
Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M., Ishwad C.S., Jarvik J.W.
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003
Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W., Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=23419152; DOI=10.1186/gm419
Lechner M., Fenton T., West J., Wilson G., Feber A., Henderson S., Thirlwell C., Dibra H.K., Jay A., Butcher L.M., Chakravarthy A.R., Gratrix F., Patel N., Vaz F., O'Flynn P., Kalavrezos N., Teschendorff A.E., Boshoff C., Beck S.
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Genome Med. 5:15.1-15.16(2013)

PubMed=24403267; DOI=10.1002/cam4.151
Kawakami H., Okamoto I., Terao K., Sakai K., Suzuki M., Ueda S., Tanaka K., Kuwata K., Morita Y., Ono K., Nishio K., Nishimura Y., Doi K., Nakagawa K.
Human papillomavirus DNA and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma.
Cancer Med. 2:933-941(2013)

Cross-references
Cell line collections (Providers) DSMZ; ACC-865
Cell line databases/resources cancercelllines; CVCL_C030
DSMZCellDive; ACC-865
Encyclopedic resources Wikidata; Q54991573
Gene expression databases GEO; GSM937838
GEO; GSM937839
Polymorphism and mutation databases IARC_TP53; 18353
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number17