Cellosaurus cell line UPCI-SCC-016 (CVCL

Cellosaurus UPCI-SCC-016 (CVCL_C027)

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Cell line name

UPCI-SCC-016

Synonyms

UPCI:SCC016; UPCISCC016; SCC016

Accession

CVCL_C027

Resource Identification Initiative

To cite this cell line use: UPCI-SCC-016 (RRID:CVCL_C027)

Comments

Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: ~50 hours (DSMZ=ACC-884).
Omics: Proteomics; Expression; Reverse-phase protein array.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=12872257).

Disease

Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_2221 ! UPCI-SCC-026

Sex of cell

Female

Age at sampling

82Y

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-884

Markers:

Amelogenin	X
CSF1PO	10,12
D2S1338	20
D3S1358	15,16
D5S818	13
D7S820	8,10
D8S1179	13
D13S317	8
D16S539	11,12
D18S51	17
D19S433	13,15
D21S11	29,31
FGA	23,25
Penta D	9,11
Penta E	10,13
TH01	9.3,10
TPOX	8
vWA	15

Web pages

Info; MCLP; -; https://tcpaportal.org/mclp/

Publications

PubMed=12872257; DOI=10.1002/humu.10248
Cheryl A. Telmer, Ji-Yan An, David E. Malehorn, Xue-Mei Zeng, Susanne M. Gollin, Chandramohan S. Ishwad, Jonathan W. Jarvik;
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
Jason S. White, Joel L. Weissfeld, Camille C.R. Ragin, Karen M. Rossie, Christa Lese Martin, Michele Shuster, Chandramohan S. Ishwad, John C. Law, Eugene Nicholas Myers, Jonas T. Johnson, Susanne M. Gollin;
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065
Christa Lese Martin, Shalini C. Reshmi, Thomas Ried, William Gottberg, John W. Wilson, Jaya K. Reddy, Poornima Khanna, Jonas T. Johnson, Eugene Nicholas Myers, Susanne M. Gollin;
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, Agda Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-884

Cell line databases/resources

Cell_Model_Passport; SIDM01827
DSMZCellDive; ACC-884

Encyclopedic resources

Wikidata; Q54991564

Polymorphism and mutation databases

IARC_TP53; 18350

Entry history

Entry creation

06-Jun-2012

Last entry update

10-Apr-2025

Version number