ID   UPCI-SCC-016
AC   CVCL_C027
SY   UPCI:SCC016; UPCISCC016; SCC016
DR   Cell_Model_Passport; SIDM01827
DR   DSMZ; ACC-884
DR   DSMZCellDive; ACC-884
DR   IARC_TP53; 18350
DR   Wikidata; Q54991564
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=17681875;
RX   PubMed=28196595;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Caucasian.
CC   Doubling time: ~50 hours (DSMZ=ACC-884).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=12872257).
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
ST   Source(s): DSMZ=ACC-884
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 8
ST   D16S539: 11,12
ST   D18S51: 17
ST   D19S433: 13,15
ST   D21S11: 29,31
ST   D2S1338: 20
ST   D3S1358: 15,16
ST   D5S818: 13
ST   D7S820: 8,10
ST   D8S1179: 13
ST   FGA: 23,25
ST   Penta D: 9,11
ST   Penta E: 10,13
ST   TH01: 9.3,10
ST   TPOX: 8
ST   vWA: 15
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_2221 ! UPCI-SCC-026
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 20
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//