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Cellosaurus MaNRAS2 (CVCL_B9UU)

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Cell line name MaNRAS2
Synonyms 1014
Accession CVCL_B9UU
Resource Identification Initiative To cite this cell line use: MaNRAS2 (RRID:CVCL_B9UU)
Comments Characteristics: Established from a tumor engrafted into 2-month-old C57BL/6 mice and collected after growth (PubMed=31251472).
Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:7989; NRAS (Note=With p.Gln61Lys).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: ((C57BL/6J x DBA/2) Tg(Tyr-NRAS*Q61K)1Bee transgenic x C57BL/6J) F2.
Sex of cell Female
Age at sampling 1Y
Category Cancer cell line
Publications

PubMed=31251472; DOI=10.1111/pcmr.12807
Valerie Petit, Jeremy Raymond, Christophe Alberti, Marie Pouteaux, Stuart J. Gallagher, Mai Q. Nguyen, Andrew E. Aplin, Veronique Delmas, Lionel Larue;
C57BL/6 congenic mouse NRAS(Q61K) melanoma cell lines are highly sensitive to the combination of Mek and Akt inhibitors in vitro and in vivo.
Pigment Cell Melanoma Res. 32:829-841(2019)

Cross-references
Encyclopedic resources Wikidata; Q112930069
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number5