ID   MaNRAS2
AC   CVCL_B9UU
SY   1014
DR   Wikidata; Q112930069
RX   PubMed=31251472;
CC   Characteristics: Established from a tumor engrafted into 2-month-old C57BL/6 mice and collected after growth (PubMed=31251472).
CC   Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:7989; NRAS (Note=With p.Gln61Lys).
CC   Breed/subspecies: ((C57BL/6J x DBA/2) Tg(Tyr-NRAS*Q61K)1Bee transgenic x C57BL/6J) F2.
DI   NCIt; C21790; Mouse melanoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   1Y
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 19-12-24; Version: 5
//
RX   PubMed=31251472; DOI=10.1111/pcmr.12807;
RA   Petit, Valerie
RA   Raymond, Jeremy
RA   Alberti, Christophe
RA   Pouteaux, Marie
RA   Gallagher, Stuart J.
RA   Nguyen, Mai Q.
RA   Aplin, Andrew E.
RA   Delmas, Veronique
RA   Larue, Lionel
RT   "C57BL/6 congenic mouse NRAS(Q61K) melanoma cell lines are highly
RT   sensitive to the combination of Mek and Akt inhibitors in vitro and in
RT   vivo.";
RL   Pigment Cell Melanoma Res. 32:829-841(2019).
//