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Cellosaurus UBT-5 (CVCL_B972)

[Text version]
Cell line name UBT-5
Accession CVCL_B972
Resource Identification Initiative To cite this cell line use: UBT-5 (RRID:CVCL_B972)
Comments Population: Japanese and Korean.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1066; BMI1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mesenchymal stem cell of bone marrow; CL=CL_0002540.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6F32 (H4-1 [Human bone marrow])
Sex of cell Female
Age at sampling 91Y
Category Telomerase immortalized cell line
Publications

PubMed=15293342; DOI=10.1002/jgm.583
Yukiji Takeda, Taisuke Mori, Hideaki Imabayashi, Tohru Kiyono, Satoshi Gojo, Shunichirou Miyoshi, Naoko Hida, Makoto Ita, Kaoru Segawa, Satoshi Ogawa, Michiie Sakamoto ...Show all 13 authors... , Shinobu Nakamura, Akihiro Umezawa; Show fewer authors
Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation?
J. Gene Med. 6:833-845(2004)

PubMed=15923633; DOI=10.1128/mcb.25.12.5183-5195.2005; PMCID=PMC1140572
Taisuke Mori, Tohru Kiyono, Hideaki Imabayashi, Yukiji Takeda, Kohei Tsuchiya, Shunichirou Miyoshi, Hatsune Makino, Kenji Matsumoto, Hirohisa Saito, Satoshi Ogawa, Michiie Sakamoto ...Show all 13 authors... , Jun-ichi Hata, Akihiro Umezawa; Show fewer authors
Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential.
Mol. Cell. Biol. 25:5183-5195(2005)

Cross-references
Encyclopedic resources Wikidata; Q54973900
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number13