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Cellosaurus JAR-Smad3/c (CVCL_B7MU)

[Text version]
Cell line name JAR-Smad3/c
Synonyms JAR-smad3/c
Accession CVCL_B7MU
Resource Identification Initiative To cite this cell line use: JAR-Smad3/c (RRID:CVCL_B7MU)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6769; SMAD3.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Disease Gestational choriocarcinoma (NCIt: C4646)
Gestational choriocarcinoma (ORDO: Orphanet_99926)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0360 (JAR)
Sex of cell Male
Age at sampling Fetus
Category Cancer cell line
Publications

PubMed=12074587; DOI=10.1016/S0006-291X(02)00605-8
Guo-Xiong Xu, Chandan Chakraborty, Peeyush K. Lala;
Restoration of TGF-beta regulation of plasminogen activator inhibitor-1 in Smad3-restituted human choriocarcinoma cells.
Biochem. Biophys. Res. Commun. 294:1079-1086(2002)

PubMed=15150278; DOI=10.1074/jbc.M400641200
Sadia Munir, Guo-Xiong Xu, Yao-Jiong Wu, Burton Yang, Peeyush K. Lala, Chun Peng;
Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells.
J. Biol. Chem. 279:31277-31286(2004)

Cross-references
Encyclopedic resources Wikidata; Q112929892
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number6