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Cellosaurus Y-79 Eto-R (CVCL_B7IG)

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Cell line name Y-79 Eto-R
Synonyms Y-79 etoposide-resistant; Y-79 Etop
Accession CVCL_B7IG
Resource Identification Initiative To cite this cell line use: Y-79 Eto-R (RRID:CVCL_B7IG)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_4911; Etoposide (VP-16).
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1893 (Y-79)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line
Publications

PubMed=29192327; DOI=10.3892/or.2017.6100; PMCID=PMC5783599
Maike Anna Busch, David Papior, Harald Stephan, Nicole Dunker;
Characterization of etoposide- and cisplatin-chemoresistant retinoblastoma cell lines.
Oncol. Rep. 39:160-172(2018)

Cross-references
Encyclopedic resources Wikidata; Q112930588
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number5