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Cellosaurus CAE606 (CVCL_B7GW)

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Cell line name CAE606
Accession CVCL_B7GW
Resource Identification Initiative To cite this cell line use: CAE606 (RRID:CVCL_B7GW)
Comments Doubling time: 25.8 hours (PubMed=35349366).
Derived from site: In situ; Ear, auditory canal; UBERON=UBERON_0001352.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Trp110Ter (c.329G>A); ClinVar=VCV000376304; Zygosity=Homozygous (PubMed=35349366).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu28Lysfs*16 (c.81delT); Zygosity=Homozygous (PubMed=35349366).
Disease External auditory canal squamous cell carcinoma (NCIt: C202594)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): PubMed=35349366

Markers:
AmelogeninX
CSF1PO12
D3S135815
D5S81813
D7S82010,11
D8S117913
D13S31712,13
D16S5399,13
D18S5114
D21S1130,33.2
FGA22,23
Penta D11,12
Penta E11
TH016
TPOX8,11
vWA17,18

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Publications

PubMed=35349366; DOI=10.1177/01945998221089186
Rocio Garcia-Marin, Virginia N. Cabal, Carmen Fernandez-Cedron Bermejo, Cristina Riobello, Laura Suarez-Fernandez, Helena Codina-Martinez, Ainhoa Navarro-Garcia, Sara Lucila Lorenzo-Guerra, Jorge Garcia-Martinez, Blanca Vivanco, Fernando Lopez ...Show all 13 authors... , Jose Luis Llorente, Mario A.J.A. Hermsen; Show fewer authors
A novel external auditory canal squamous cell carcinoma cell line sensitive to CDK4/6 inhibition.
Otolaryngol. Head Neck Surg. 168:729-737(2023)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7GW
Encyclopedic resources Wikidata; Q112929358
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7