ID   CAE606
AC   CVCL_B7GW
DR   cancercelllines; CVCL_B7GW
DR   Wikidata; Q112929358
RX   PubMed=35349366;
CC   Doubling time: 25.8 hours (PubMed=35349366).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Trp110Ter (c.329G>A); ClinVar=VCV000376304; Zygosity=Homozygous (PubMed=35349366).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu28Lysfs*16 (c.81delT); Zygosity=Homozygous (PubMed=35349366).
CC   Derived from site: In situ; Ear, auditory canal; UBERON=UBERON_0001352.
ST   Source(s): PubMed=35349366
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12,13
ST   D16S539: 9,13
ST   D18S51: 14
ST   D21S11: 30,33.2
ST   D3S1358: 15
ST   D5S818: 13
ST   D7S820: 10,11
ST   D8S1179: 13
ST   FGA: 22,23
ST   Penta D: 11,12
ST   Penta E: 11
ST   TH01: 6
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C202594; External auditory canal squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 19-12-24; Version: 7
//
RX   PubMed=35349366; DOI=10.1177/01945998221089186;
RA   Garcia-Marin R., Cabal V.N., Fernandez-Cedron Bermejo C., Riobello C.,
RA   Suarez-Fernandez L., Codina-Martinez H., Navarro-Garcia A.,
RA   Lorenzo-Guerra S.L., Garcia-Martinez J., Vivanco B., Lopez F.,
RA   Llorente J.L., Hermsen M.A.J.A.;
RT   "A novel external auditory canal squamous cell carcinoma cell line
RT   sensitive to CDK4/6 inhibition.";
RL   Otolaryngol. Head Neck Surg. 168:729-737(2023).
//