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Cellosaurus MPT-S1 (CVCL_B7GV)

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Cell line name MPT-S1
Accession CVCL_B7GV
Resource Identification Initiative To cite this cell line use: MPT-S1 (RRID:CVCL_B7GV)
Comments Population: Chinese.
Characteristics: Established from a nude mouse xenograft.
Doubling time: 2-3 days (PubMed=35365682).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Mutation; HGNC; HGNC:7133; KMT2D; Simple; c.6079_6082delAATT; Zygosity=Heterozygous (PubMed=35365682).
  • Mutation; HGNC; HGNC:11957; MED12; Simple; p.Gly44Asp (c.131G>A); ClinVar=VCV000092220; Zygosity=Heterozygous (PubMed=35365682).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.1530_1531delAG; Zygosity=Heterozygous (PubMed=35365682).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.1588_1589delAA; Zygosity=Heterozygous (PubMed=35365682).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.750_754delinsA; Zygosity=Heterozygous (PubMed=35365682).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu252del (c.754_756delCTC); ClinVar=VCV000998484; Zygosity=Heterozygous (PubMed=35365682).
Disease Malignant breast phyllodes tumor (NCIt: C4504)
Phyllodes tumor of the breast (ORDO: Orphanet_180261)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): PubMed=35365682

Markers:
AmelogeninX
CSF1PO12
D1S165611,16
D2S44112
D2S133823
D3S135815,16
D5S81811
D7S82012
D8S117911,13
D10S124813,14
D12S39121
D13S3179,12
D16S53910,11
D18S5118
D19S43313.2
D21S1129,30
D22S104514
DYS3919
FGA19
Penta D9,14
Penta E11,19
TH019
TPOX8,9
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=35365682; DOI=10.1038/s41523-022-00413-1; PMCID=PMC8975864
Dave Yong Xiang Ng, Zhi-Mei Li, Elizabeth Lee, Jessica Sook Ting Kok, Jing Yi Lee, Joanna Koh, Cedric Chuan-Young Ng, Abner Herbert Lim, Wei Liu, Sheng Rong Ng, Kah Suan Lim ...Show all 21 authors... , Xi Xiao Huang, Jing Han Hong, Pei-Yong Guan, Yi-Rong Sim, Aye Aye Thike, Nur Diyana Md Nasir, Shang Li, Puay Hoon Tan, Bin Tean Teh, Jason Yong-Sheng Chan; Show fewer authors
Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor.
NPJ Breast Cancer 8:44.1-44.7(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7GV
Encyclopedic resources Wikidata; Q112930125
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number7