ID   MPT-S1
AC   CVCL_B7GV
DR   cancercelllines; CVCL_B7GV
DR   Wikidata; Q112930125
RX   PubMed=35365682;
CC   Population: Chinese.
CC   Characteristics: Established from a nude mouse xenograft.
CC   Doubling time: 2-3 days (PubMed=35365682).
CC   Sequence variation: Mutation; HGNC; 7133; KMT2D; Simple; c.6079_6082delAATT; Zygosity=Heterozygous (PubMed=35365682).
CC   Sequence variation: Mutation; HGNC; 11957; MED12; Simple; p.Gly44Asp (c.131G>A); ClinVar=VCV000092220; Zygosity=Heterozygous (PubMed=35365682).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; c.1530_1531delAG; Zygosity=Heterozygous (PubMed=35365682).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; c.1588_1589delAA; Zygosity=Heterozygous (PubMed=35365682).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Leu252del (c.754_756delCTC); ClinVar=VCV000998484; Zygosity=Heterozygous (PubMed=35365682).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.750_754delinsA; Zygosity=Heterozygous (PubMed=35365682).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
ST   Source(s): PubMed=35365682
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 13,14
ST   D12S391: 21
ST   D13S317: 9,12
ST   D16S539: 10,11
ST   D18S51: 18
ST   D19S433: 13.2
ST   D1S1656: 11,16
ST   D21S11: 29,30
ST   D22S1045: 14
ST   D2S1338: 23
ST   D2S441: 12
ST   D3S1358: 15,16
ST   D5S818: 11
ST   D7S820: 12
ST   D8S1179: 11,13
ST   DYS391: 9
ST   FGA: 19
ST   Penta D: 9,14
ST   Penta E: 11,19
ST   TH01: 9
ST   TPOX: 8,9
ST   vWA: 14,16
DI   NCIt; C4504; Malignant breast phyllodes tumor
DI   ORDO; Orphanet_180261; Phyllodes tumor of the breast
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   51Y
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 5
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RX   PubMed=35365682; DOI=10.1038/s41523-022-00413-1; PMCID=PMC8975864;
RA   Ng D.Y.X., Li Z.-M., Lee E., Kok J.S.T., Lee J.Y., Koh J., Ng C.C.-Y.,
RA   Lim A.H., Liu W., Ng S.R., Lim K.S., Huang X.X., Hong J.H., Guan P.-Y.,
RA   Sim Y.-R., Thike A.A., Md Nasir N.D., Li S., Tan P.H., Teh B.T.,
RA   Chan J.Y.-S.;
RT   "Therapeutic and immunomodulatory potential of pazopanib in malignant
RT   phyllodes tumor.";
RL   NPJ Breast Cancer 8:44.1-44.7(2022).
//